Our Work — Selected Publications

Microbiome Profiling

Dougherty MW, Valdés-Mas R, Wernke KM, Gharaibeh RZ, Yang Y, Brant JO, Riva A, Muehlbauer M, Elinav E, Puschhof J, Herzon SB, Jobin C. The microbial genotoxin colibactin exacerbates mismatch repair mutations in colorectal tumors. Neoplasia. 2023 Sep;43:100918. PMID: 37499275.

Microbiome & Host Multi-Omics

Gibbons JA, Worthington LM, Chiu EG, Kates HR, Carter RR, Nelson R, Zhang M, Garrett TJ, Ho TTB. Severe anemia in preterm infants associated with increased bacterial virulence potential. Pediatr Res. 2025 Jun;97(7):2415-2422. PMID: 39438713.

Tasci E, Popa M, Zhuge Y, Chappidi S, Zhang L, Cooley Zgela T, Sproull M, Mackey M, Kates HR, Garrett TJ, Camphausen K, Krauze AV. MetaWise: Combined Feature Selection and Weighting Method to Link the Serum Metabolome to Treatment Response. Int J Mol Sci. 2024 Oct 11;25(20). PMID: 39456748.

Epigenomics & Chromatin Accessibility

Brant JO, Gauthier M-PL, Rodhouse CE, Wu R, Hernández-Ríos M, Zeumer-Spataro L, Dirain ML, Ungaro RF, Rocha IL, Wiggins WB, Charles AM, Xiao F, Bible LE, Mohr AM, Larson SD, Rincon JC, Wallet SM, Brusko MA, Loftus TJ, Moldawer LL, Mathews CE, Bacher R, Cai G, Maile R, Efron PA, Kladde MP. Divergent chromatin remodeling trajectories in CD66b⁺ MDSCs distinguishes recovery from chronic critical illness after sepsis. bioRxiv, in revision at Science Translational Medicine.

Brant JO, Khan Z, Ju L-S, Yuan Q, Zhang Y, Gravenstein N, Seubert CN, Martynyuk AE. Intergenerational Epigenomic and Transcriptomic Effects of Neonatal Parental Exposure to the General Anesthetic Sevoflurane. In revision, Frontiers in Genetics.

Bulk RNA-seq & Immune Deconvolution

Tithi TI, Mo J, Borcherding N, Jo S, Kates HR, Cho E, Cash KE, Honda M, Wang L, Ahmed KK, Shirlekar K, Chen L, Gibson-Corley K, Weigel R, Spies M, Kolb R, Zhang W. The distinct roles of MSH2 and MLH1 in basal-like breast cancer and immune modulation. bioRxiv. 2025 Mar 13. PMID: 37745359.

Gobin C, Inkabi S, Lattimore CC, Gu T, Menefee JN, Rodriguez M, Kates H, Fields C, Bian T, Silver N, Xing C, Yates C, Renne R, Xie M, Fredenburg KM. Investigating miR-9 as a mediator in laryngeal cancer health disparities. Front Oncol. 2023;13:1096882. PMID: 37081981.

Multi-Omics Integration & Reproducible Pipelines

Kates HR. metabo-reportR. Version 1.0. GitHub; 2026. https://github.com/HeatherKates/metabo-reportR